This Seeking Tech guide will explain how you can beat the Blister Borne at the Chapel as Leon without taking damage in Resident Evil Requiem.
To do so, follow the video and text guides below:
The Blister Borne has multiple weak points. Every time you pop one of his weak points, however, zombies might show up. He will also turn any nearby zombies into Blister Heads.
To avoid getting surrounded, hide behind the podium when the fight starts. This will give you some time to hit the weak spots on the Blister Borne. Use your handgun to shoot a bullet or two to make these spots swell up. Just make sure you don’t destroy these spots, or you will summon the zombies and/or Blister Heads.
Once the boss gets close to you at the podium, quickly rush to the staircase to the second floor. From there, wait until the boss chases you before you drop down through the gap of the railing to the first floor.
He should follow but end up getting stunned for a few seconds when he lands on the first floor, exposing his back weak spot for you to swell up if you haven’t done so already.
Once you hit all the weak spots at least once with your handgun, bait the boss again to drop down from the second floor. Once he is stunned, rush back to the second-floor spot with the opened railing and then use your shotgun or sniper to destroy as many weak spots as you can.
If zombies and Blister Heads start to appear, shoot the red canister if they are nearby. You can use grenades as well to quickly kill them so that you won’t get overwhelmed.
Try to stay on the second floor for as long as possible since it is the safest area in the fight. If you must drop down, try to get back to the second floor again as quickly as possible.
Towards the end of the fight, the stairway to the second floor will be blocked unless you stay up there. If you are forced to face the boss and his minions on the first floor, try to use any throwable weapons on the floor to stun them. You can then follow up with a melee attack. You will need to kill the boss as well as any of the remaining minions.